Presentations

The Liver Meeting - American Association for the Study of Liver Disease, November 2017

Identification of Novel Targets for Nonalcoholic Steatohepatitis Using a Human Surrogate System (Presidential Award)

Charles River Laboratory World Congress on Animal Models in Drug Discovery & Development, September 2017

Patient in a Dish - Non-alcoholic Steatohepatitis (NASH) and Beyond

13th Annual Middle East Metabolic Group Meeting, Amman, Jordan - October 2016

The utility of patient-derived hepatocytes for developing therapies in proprionic acidemia

Charles River Labs Rare Disease Drug Discovery Symposium, New York, NY - October 2016

The utility of patient-derived hepatocytes for developing therapies in proprionic acidemia

The Society for the Study of Inborn Errors of Metabolism (SSIEM), Rome,Italy - September 2016

The utility of patient-derived hepatocytes for developing therapies in proprionic acidemia

Society for Inherited Metabolic Disorders, April 2016

Recapitulation of Metabolic Defects in a Model of Propionic Acidemia Using Patient-Derived Primary Hepatocytes.

 

Predictive Modeling and Characterization of Altered Metabolic Activity in Propionic Acidemia

 

Quantitation of Acyl-Coenzyme A and Acyl-Carnitine in Primary Human Hepatocytes from Propionic Acidemia Patients (oral talk)

American Association of the Study of Liver Diseases, November 2015

Transcriptomic Analysis Of Human Hepatocytes In 3-Dimensional Cultures With Maintained Perfusion And Transport Offers Insights Into The Pharmacotoxicology Of Clinically Relevant Concentrations Of Obeticholic Acid

54th Annual Meeting of the Society of Toxicology, San Diego, CA, March 22-26, 2015 (abstract 2574)
Transcriptional Profiling Suggests that Nevirapine Mediates Effects on Primary Human Hepatocytes Necessary for Immune-Mediated Toxicity

American College of Rheumatology Annual Meeting, Boston, MA, November 2014 (abstract 439)
The Anti-IL-6 Antibody Sirukumab Inhibits Vascular Inflammation in a Human Surrogate Model of Atherosclerosis

NCI Investor Forum, Santa Clara, CA, November 13, 2014
The HemoShear Tumor Microenvironment Discovery Accelerator

Arteriosclerosis, Thrombosis, and Vascular Biology 2014 Annual Conference, Toronto, Canada, May 2014 (abstract 137)
The Response of an In Vitro Cynomolgus Macaque System to Statin Treatments Mirrors the Human In Vitro System and Clinical Outcomes

Annual Meeting of the Society of Toxicology, Phoenix, AZ, March 2014 (abstract 1129a)
Altered Hemodynamics Play a Critical Role in Fenoldopam-Induced Mesenteric Vasculitis in the Rat

American Association for the Study of Liver Disease, Washington, DC, November 2013
Controlled Hemodynamics Maintains Metabolic and Hepatitis C Virus Supportive Phenotype In Primary Human Hepatocytes

Arteriosclerosis, Thrombosis, and Vascular Biology Annual Meeting, Lake Buena Vista, FL, May 2013 (abstract 310)
GLP-1 Cleavage Product (9-36)-NH2 Exerts Pro-Survival Effects on Smooth Muscle Cells in Advanced Inflammatory Hemodynamics Conditions

Arteriosclerosis, Thrombosis, and Vascular Biology Annual Meeting, Lake Buena Vista, FL, May 2013 (abstract 133)
Hemodynamic Environment-dependent Effects of Human HDL and oxHDL on Vessel Wall Inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology Annual Meeting, Lake Buena Vista, FL, May 2013 (abstract 73)
Atrial Fibrillation-induced Changes in Left Atrial Hemodynamics Directly Impact the Thrombotic Potential of Human Primary Endothelial Cell Cultures

Arteriosclerosis, Thrombosis, and Vascular Biology Annual Meeting, Chicago, IL, April 2012 (abstract 521)
The Thrombotic Potential of the Endothelium Is Regulated by Hemodynamic Flow

Arteriosclerosis, Thrombosis, and Vascular Biology Annual Meeting, Chicago, IL, April 2012 (abstract 179)
Atheroprone Hemodynamics and Oxidized Phospholipids Enhance Endothelial and Smooth Muscle Inflammatory Signaling